Phenotypic detection of some virulence factors of uropathogenic Escherichia coli isolated from recurrent urinary tract infection patients

Abstract

Urinary tract infections (UTIs) are health growing problem in patients attending some hospitals in worldwide, to shed light on this subject, present study was done to detect some virulence factors of E. coli isolated from patients with recurrent urinary tract infection (RUTI) This study included 130 patients with RUTI, and 50 healthy persons as a control of both genders (aged 6-70 years) attending Al-Zahra Teaching Hospital in Al-Kut/Wassite governorate and Al-Harery Teaching Hospital of specialized surgeries/Baghdad during beginning of September 2009 to end of April 2011. Intracellular bacterial communities (ICBC) (namely E.coli) was isolated from (68/130) 53% from patients with RUTI. These bacteria showed differences in response to antibiotics which was used for treatment, Ciprofloxin, Amikacin and Gentamicin provide good efficacy against E.coli isolated from patients with recurrent UTI. Results of phenotipical studies on virulence factors of E.coli the revealed that 50% of RUTI isolates produced P-fimbria, 10.3% with S-fimbria, 36.8% have Dr-fimbria, 78% have type 1 fimbria and 22.1% of them produced aerobactin and all isolates gave negative results for hemolysin production.