Abstract

Objective Infants infected with HIV-1 fail to contain viral replication as efficiently as adults. In the absence of antiretroviral therapy (ART), opportunistic infections are common and mortality rates range between 10–45% in HIV-infected infants. To understand better the factors underlying rapid infant HIV-1 progression, we examined HIV-specific CD8 T cells during the acute and chronic phases of infection.

Highlights

  • Fifth Dominique Dormont International Conference

  • Infants infected with HIV-1 fail to contain viral replication as efficiently as adults

  • To understand better the factors underlying rapid infant HIV-1 progression, we examined HIV-specific CD8 T cells during the acute and chronic phases of infection

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Summary

Open Access

Phenotypic characterization of HIV-specific CD8 T cells during acute infant HIV infection. Host-Pathogen Interactions in Chronic Infections Meeting abstracts – A single PDF containing all abstracts in this Supplement is available here. http://www.biomedcentral.com/content/pdf/1742-4690-6-S1-info.pdf

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