Phenotypic Changes in Staphylococcal Cell Surface Characteristics Associated with Growth in Human Peritoneal Dialysis Fluid

Stephen P. Denyer,David G. E. Smith,Martyn C. Davies,Mark H. Wilcox,Jacqueline A. Evans,Paul Williams,Roger G. Finch

doi:10.1007/978-1-4471-3454-1_54

Phenotypic Changes in Staphylococcal Cell Surface Characteristics Associated with Growth in Human Peritoneal Dialysis Fluid

Stephen P. Denyer, David G. E. Smith + Show 5 more

https://doi.org/10.1007/978-1-4471-3454-1_54

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Publication Date: Jan 1, 1990

Citations: 5

#Human Peritoneal Dialysate #Iron-repressible Membrane Proteins + Show 8 more

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Abstract

Growth of Staphylococcus epidermidis clinical isolates in pooled human peritoneal dialysate (HPD) resulted in the generation of surface characteristics unique to this environment. Comparison of cell wall and membrane protein profiles of bacteria grown in HPD or Nutrient Broth revealed considerable differences. In particular, two highly immunogenic, iron-repressible membrane proteins, which may function as siderophore receptors, were induced in HPD-grown cells.

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