Abstract
Background Human type 1A diabetes (T1AD) has a broad spectrum of clinical presentations, which may be associated with the severity of autoimmune response and consequently, different levels of pancreatic beta cells destruction. The T1AD presents a partial remission phase. The remission phase is classically a short period in childhood-onset diabetes, but longer periods may occur especially in young.
Highlights
Human type 1A diabetes (T1AD) has a broad spectrum of clinical presentations, which may be associated with the severity of autoimmune response and different levels of pancreatic beta cells destruction
Immunophenotyping at the time of diagnosis and during followup may help the definition of both T1AD clinical subtypes and remission period
After a Lyse/Wash protocol, cells were stained for CD4, FoxP3, CTLA4, CD25
Summary
Human type 1A diabetes (T1AD) has a broad spectrum of clinical presentations, which may be associated with the severity of autoimmune response and different levels of pancreatic beta cells destruction. Phenotype of regulatory T cells in human type 1 diabetes at diagnosis and partial remission phase Daniela da Silva Camilo, Adriel Santos Moraes, Fernando Pradella, Paula Giovana Russini, Alliny Carolina Dionete Lima, Ana Leda Longhini, Maria Fernanda Vanti Macedo Paulino, Sofia Helena Valente de Lemos Marini, Gil Guerra Jr, Elizabeth João Pavin, Candida Parisi, Alessandro dos Santos Farias, Leonilda Maria Barbosa dos Santos, Walkyria Mara Gonçalves Volpini From 20th Brazilian Diabetes Society Congress Porto Alegre, Brazil.
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