Phenotype/Genotype Discrepancy of DPD Deficiency Screening in a Patient With Severe Capecitabine Toxicity: A Case Report

Abstract

Article Tools CASE REPORTS Article Tools OPTIONS & TOOLS Export Citation Track Citation Add To Favorites Rights & Permissions COMPANION ARTICLES No companion articles ARTICLE CITATION DOI: 10.1200/PO.22.00508 JCO Precision Oncology no. 7 (2023) e2200508. Published online March 16, 2023. Phenotype/Genotype Discrepancy of DPD Deficiency Screening in a Patient With Severe Capecitabine Toxicity: A Case Report François Poumeaud, MD1xFrançois PoumeaudSearch for articles by this author; Florence Dalenc, MD, PhD1,2xFlorence DalencSearch for articles by this author; Quentin Mathevet, PharmD3xQuentin MathevetSearch for articles by this author; Aurélie Brice, BTEC3xAurélie BriceSearch for articles by this author; Audrey Eche-Gass, MD1xAudrey Eche-GassSearch for articles by this author; Eleonora De Maio D'Esposito, MD1xEleonora De Maio D'EspositoSearch for articles by this author; Clémence Brac-de-la-Perriere, MD1xClémence Brac-de-la-PerriereSearch for articles by this author; and Fabienne Thomas, PharmD, PhD1,2xFabienne ThomasSearch for articles by this author Show More 1Department of Medical Oncology, Institut Claudius Regaud, IUCT—Oncopole, Toulouse, France2Centre de Recherches en Cancérologie de Toulouse, Inserm UMR1037, Université Toulouse III-Paul Sabatier, Toulouse, France3Department of Pharmacology, Institut Claudius Regaud, IUCT-Oncopole, Toulouse, France https://doi.org/10.1200/PO.22.00508 First Page Full Text PDF Figures and Tables © 2023 by American Society of Clinical OncologyAUTHOR CONTRIBUTIONSConception and design: Francois Poumeaud, Quentin Mathevet, Eleonora De Maio D'Esposito, Fabienne ThomasCollection and assembly of data: Francois Poumeaud, Florence Dalenc, Audrey Eche-Gass, Fabienne ThomasData analysis and interpretation: Francois Poumeaud, Florence Dalenc, Aurélie Brice, Audrey Eche-Gass, Clémence Brac-de-la-Perrière, Fabienne ThomasManuscript writing: All authorsFinal approval of manuscript: All authorsAccountable for all aspects of the work: All authorsAUTHORS' DISCLOSURES OF POTENTIAL CONFLICTS OF INTERESTThe following represents disclosure information provided by authors of this manuscript. All relationships are considered compensated unless otherwise noted. Relationships are self-held unless noted. I = Immediate Family Member, Inst = My Institution. Relationships may not relate to the subject matter of this manuscript. For more information about ASCO's conflict of interest policy, please refer to www.asco.org/rwc or ascopubs.org/po/author-center.Open Payments is a public database containing information reported by companies about payments made to US-licensed physicians (Open Payments).Clémence Brac-de-la-PerriereTravel, Accommodations, Expenses: Viatris, MSD, Lilly, AmgenNo other potential conflicts of interest were reported.