PHENOTYPE DIFFERENCE BETWEEN GENOTYPE OF PLAKOPHILIN-2 MUTATION AND DESMOGLEIN-2 MUTATION IN SYMPTOMATIC CHINESE PATIENTS WITH ARRHYTHMOGENIC RIGHT VENTRICULAR DYSPLASIA/CARDIOMYOPATHY-A REPORT FROM CHINESE ARVD REGISTRY

Abstract

ObjectivesArrhythmogenic Right Ventricular Dysplasia/cardiomyopathy (ARVD/C) is an inherited heart muscle disease associated mainly with the mutations of desmosome. Plakophilin-2 (PKP2) and desmoglein-2 (DSG-2) are reported as the most two common...