Phenolkampfer関節内注入の実験的並びに臨床的研究

Abstract

Correlations between intraarticular changes and local findings and skin surface and intraarticular temperature following Phenolcamphor injection were studied to assure the possibilities of anticipating its effects and courses following Phenolcamphor injection by measurement of temperature. Phenolcamphor were injected into knee joints of three groups of normal rabbits in which 0.25 cc and 0.5 cc of Phenolcamphor, and mixed solution of 0.25 cc of Phenolcamphor and 0.25 cc of water as control were given. Temperatnre was measured with electric thermometer.1) Close relationship were found between intraarticular changes and local findings, and skin surface and intraarticular temperature following intraarticular injection of Phenolcamphor.Temperature rose with increase of local inflammatory signs and falls with its regression and stabilized after two or three weeks.2) Parallel correlation was found between skin surface and intraarticular temperature with a little high level in the latter.3) No difference in changes of temperature was found in different amount of injected Phenolcamphor, though the Peak of temperature rise was noted slightly later in the case of a small amount of injected material than in the large amount.4) It is of significance for observation of effects and course of Phenolcamphor injection to measure skin surface and intraarticular temperature. However, it is not feasible to measure frequently intraarticular temperature and also it is hardly acceptable to inject procaine into joint for the relief of pain in measurement of intraarticular temperature. It is not applicable to clinical use, hence measurement of skin temperature should be used as substitute for it.