Abstract
ABSTRACTAlmond (Terminalia catappa) is a species used in Nigerian folkloric medicine because of its antihypertensive property. In this study, the acetylcholinesterase, arginase, phosphodiesterase-5 and angiotensin-1-converting enzyme inhibition and antioxidant properties of the phenolic-rich extracts from almond leaf and stem bark were determined. The chemical composition was evaluated using high-performance liquid chromatography. The total phenol and flavonoid contents were estimated and the antihypertensive potential was estimated by the determination of acetylcholinesterase, arginase, phosphodiesterase-5 and angiotensin-1-converting enzyme inhibition in vitro. Three assays were used for the evaluation of antioxidant properties of the extracts. Eleven and eight phenolic compounds were detected in leaf and stem bark respectively. The phenolic-rich extracts showed remarkable enzyme inhibition activity in concentration dependent manner, with high antioxidant activities. Almond leaf and stem bark can serve as potential natural source for the development of a novel antihypertensive agent.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
