Abstract
Since C. platycarpos contains a wide variety of antioxidants, in the present study total flavonoid and phenolic acid content as well as antioxidative activity of various C. platycarpos extracts were investigated. The results obtained show a significant polyphenol content and antioxidant activity of the investigated plant. Moreover, a positive correlation between antioxidant activity and content of flavonoids and phenolic acids was found, indicating the responsibility of these compounds for the antioxidant effectiveness of C. platycarpos extracts and making C. platycarpos a good potential source of natural antioxidants.
Highlights
IntroductionCertain tumors are very amenable to treatment, malignant diseases are still one of the leading causes of death in the World
Malignant diseases are progressive and, if untreated, result in death in most cases
The results indicated that C. platycarpos water extract remarkably increased the antitumor activity of the hyperthermic chemotherapy as well as the survival of mice with peritoneal carcinomatosis [2]
Summary
Certain tumors are very amenable to treatment, malignant diseases are still one of the leading causes of death in the World. A flavonoid glycoside, chrysoeriol-7-O-rutinoside, that was found to be characteristic for the investigated plant was isolated and structurally characterized by mass spectrometry. Phenolic compounds, including both phenolic acids and flavonoids, are considered to be the major bioactive compounds in C. platycarpos [4,5]. Since C. platycarpos contains a wide variety of free radical-scavenging molecules, the aim of this work was to investigate total flavonoid and phenolic acid content as well as its antioxidative activity. To gain better insight into the antioxidant activity of C. platycarpos hydroxyl radical scavenging activity, scavenging effect on superoxide anion radical, the reducing power and the ability of plant extracts to chelate iron(II) ions were investigated
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