Abstract
The genus Taraxacum is a member of the family Asteraceae, subfamily Cichorioideae, tribe Lactuceae. The total number of Taraxacum in Turkey at present is 43 species. In folk medicine, this genus has been utilized for the treatment of various diseases such as dyspepsia, heartburn, spleen and liver complaints, hepatitis and anorexia. Taraxacum bessarabicum is a perennial herb growing Eastern Turkey. The isolation of sesquiterpene lactones and two phenolics has previously been reported from the roots of this species. In this work coumarins (esculetin, cichorin), flavonoids (luteolin, luteolin- 7-O-glucoside, gossypetin) and phenolic acids (p-coumaric acid, caffeic acid, ferulic acid, chlorogenic acid methyl ester, 3,5-dicaffeoylquinic acid, 3,5- dicaffeoilquinic acid methyl ester) have been isolated from the EtOAc and CHCl3 fractions of MeOH extract from the aerial parts of Taraxacum bessarabicum subsp. bessarabicum collected from Erzincan, East Anatolia. Column chromatography and preparative thin layer chromatography were used for separation of these compounds. Their structures were established conclusively by UV, ESI-MS, 1-D and 2-D NMR spectra analyses and comparison with literature data. The presence of these compounds has been shown for the first time from this species. Gossypetin, chlorogenic acid methyl ester, 3,5- dicaffeoilquinic acid methyl ester are new for the genus Taraxacum.
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