Abstract
In the present current, quercetin and its 3-O.-rutinoside, the ethyl acetate and ethanol extracts, and two new flavones from Casimiroa edulis. Llave et Lex (Rotaceae) were tested for their antioxidant activity via scavenging by the ABTS˙+ [2,2′-azinobis(3-ethylbenzothiazolone-6-sulfonic acid)]free radical. Among all the tested fractions and compounds, the ethanol extract exhibited the strongest antioxidant activity followed by EtOAc extract, giving 842 and 712 µM Trolox equivalents/g dry weight, respectively. Moderate activities were detected for the other tested materials. The two new flavones were identified as 5-methoxy-6-hydroxyflavone and its 6-O.-β.-D-glucoside. The structure elucidation was based on UV, electrospray ionization mass spectrometry (ESIMS), 1H and 13C NMR, proton-proton correlation spectroscopy (1H-1H COSY), distortionless enhancement by polarization transfer (DEPT), heteronuclear single quantum coherence (HSQC), and heteronuclear multiple bond correlations spectrum (HMBC).
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