Phenethyl-α-pyrone derivatives and cyclodipeptides from a marine algous endophytic fungus Aspergillus niger EN–13

Abstract

Two new phenethyl-α-pyrone derivatives including, isopyrophen (1) and aspergillusol (2), were characterised from the culture extract of Aspergillus niger EN–13, an endophytic fungus isolated from the inner tissue of the marine brown alga Colpomenia sinuosa. In addition, four known compounds, including a phenethyl-α-pyrone derivative (pyrophen, 3) and three cyclodipeptides (4–6), were also isolated and identified. The structures of these compounds were elucidated by spectroscopic methods.