Abstract

We study the phase separation of binary lipid mixtures that form bicontinuous cubic phases. The competition between the nonuniform Gaussian membrane curvature and line tension leads to a very rich phase diagram, where we observe symmetry breaking of the membrane morphologies and reentrant phenomena due to the formation of bridges between segregated domains. Upon increasing the line tension contribution, we also find faceting of lipid domains that we explain using a simple argument based on the symmetry of the underlying surface and topology.

Highlights

  • Introduction.—Lipid self-assembly can adopt an astonishing range of shapes and morphologies, from single bilayer structures to stacks and convoluted periodic structures [1]

  • We study the phase separation of binary lipid mixtures that form bicontinuous cubic phases

  • Upon increasing the line tension contribution, we find faceting of lipid domains that we explain using a simple argument based on the symmetry of the underlying surface and topology

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Summary

Introduction

Introduction.—Lipid self-assembly can adopt an astonishing range of shapes and morphologies, from single bilayer structures to stacks and convoluted periodic structures [1]. The competition between the nonuniform Gaussian membrane curvature and line tension leads to a very rich phase diagram, where we observe symmetry breaking of the membrane morphologies and reentrant phenomena due to the formation of bridges between segregated domains.

Results
Conclusion

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