Abstract
A swift response to stress requires global translational suppression, excepting stress proteins. Recently, Iserman et al. uncovered that stress-induced phase separation of the RNA helicase Ded1p results in translational suppression of housekeeping transcripts that contain complex 5' untranslated regions (UTRs). Stress-response transcripts with simpler 5' UTRs escape this global translational suppression.
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