Phase III randomized trial of standard fractionation radiotherapy (SFX) with concurrent cisplatin (CIS) versus accelerated fractionation radiotherapy (AFX) with panitumumab (PMab) in patients (pts) with locoregionally advanced squamous cell carcinoma of the head and neck (LA-SCCHN): NCIC Clinical Trials Group HN.6 trial.

Abstract

6000 Background: Concurrent administration of anti-EGFR monoclonal antibody with radiotherapy (RT) increases survival compared to RT alone in pts with LA-SCCHN. No prospective data are available co...