Phase II study evaluating the effect of concomitant ramucirumab (IMC-1121B; RAM) on the pharmacokinetics (PK) of paclitaxel (PTX) and the PK of RAM as monotherapy in patients (pts) with advanced malignant solid tumors.

Abstract

e13554 Background: This study evaluated the effect of RAM on the PK of PTX (Part A) and the PK of RAM as monotherapy (Part B). Methods: Key eligibility criteria included pts aged ≥18 years with met...