Phase I study of ontuxizumab, a humanized monoclonal antibody (mAb) recognizing endosialin in Japanese patients (pts) with hepatocellular carcinoma (HCC).

Abstract

2521 Background: Endosialin is a cell surface glycoprotein that is expressed on cells involved in the development of tumor vasculature, primarily pericyte and stromal fibroblast. Ontuxizumab is a h...