Abstract
Multibilayer—disk—globular micelle phase transitions were found in mixed long-chain/short-chain phospholipid systems. For long-chain lipid/bile salt mixed systems, a disk—vesicle transition occurs upon dilution or when the bile salt concentration is decreased. Structural models based on geometrical constraints are proposed for the mixed disk aggregates. These structural models predict that the size of the mixed disk aggregates depends strongly on the short-chain to long-chain concentration ratio. The phase boundaries of the disk phase region can be easily inferred from the equations governing the size dependence of the disk aggregates on the concentration ratio of the two components. A multibilayer to disk phase transition occurs when the long-chain bilayers are saturated with the short-chain amphiphiles. The size of the center planar bilayer of the disk aggregates decreases with increasing short-chain to long-chain concentration ratio until the phase limit is reached. The globular micelle to disk micelle phase transition occurs at the saturation limit of long-chain amphiphiles in the globular short-chain micelles. The proposed models are also generalized to include dilution effects.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
