Pharmacotherapy of resistant enteric pathogens in combination with medicinal plants extracts and antibiotics

Abstract

Development of resistance to the antimicrobial products has created an evolving problem that has led the clinicians to evaluate a suitable empirical therapy for bacterial diseases and also provoked the technicians and researchers at the laboratory level to rethink about the basic sample testing policies. High rate of resistant organisms develop due to their exposure to such bacteriostatic and bactericidal agents. Such strategies should be developed that have guidelines for sensible use of these antimicrobial products. On the other hand, CDC evaluated certain approvals for clinicians that could help them in the use of these products cleverly that may retard the progress, growth and spread of these resistant pathogens. These medicinal plants have biologically active compounds which have antibacterial activity against the selected multidrug resistant enteric agents which is verified and declared by different traditional healers throughout the world on the efficacies of these plants have. Acetone gave the best results with these plants as compared to alcohol and water. The active components of these plants as antibacterial formulations have shown justified results and possibly presented a best resulting product that could be of highly value in preventing such enteric ailments. These products should be labeled with respect to the names of the active components these plants have and probably present directions for their dosage. Further improvements could also be presented in the terms of formulations of these products like emulsions or suspensions that have the ability to reduce the daily dosage of these enteric ailments and volumes of the products.