Pharmacotherapy of Hypoactive Sexual Desire

Abstract

The article reports that hypoactive sexual desire occurs quite often in both sexes, but in women, such a complaint came to the first position. The article is devoted to the presentation and discussion of various medications and dietary supplements used to enhance sexual desire in women and men. Adaptogens is reported to enhance libido. Flibanserin was the first drug approved in the United States by the Food and Drug Administration (FDA) for the treatment of acquired generalized hypoactive sexual desire disorder (HSDD) in premenopausal women. Testosterone is used in men and women with a weakened libido, and Tibolone enhances sexual desire in women. Also reported on the use of bremelanotide, the second drug approved by the FDA for the treatment of acquired generalized HSDD in premenopausal women, which is also used to increase sexual desire in men. It is informed that it also increases libido in men. In addition, bupropion and its combination with trazadone have been reported to enhance libido in women. Buspirone is reportedly used to treat sexual side effects, including diminished libido, caused by antidepressants from the selective serotonin reuptake inhibitor group. It has been noted that the enhancing sex drive in men and women may cause Tribulus Terrestris L. use and drugs created on its basis (Tribestan and its analogues). To enhance the sexual desire, two combined drugs are tested: testosterone + sildenafil and testosterone + buspirone. Also named a number of biologically active supplements used to strengthen the weakened libido and eliminate other sexual dysfunctions.