Abstract
Background: Our aim was to follow up patients postoperatively to identify seizure remission and relapse after surgery, to enable individuals considering surgery to make informed choices.
 Methods: Ninteen consecutive patients operated for drug resistant Temporal lobe & extra temporal lobe epilepsy between 2019 and 2020, at our centre. All the patients had at least one year post surgery follow-up.
 Results: The mean age of study population was 20.87 ± 10.08 years. The mean age of onset of epilepsy in study population was 14.9 ± 8 years. There were no acute post operative seizures. The most common histpathological finding was hippocampal sclerosis in 15 patients. The patients were followed up and 15 were in the class 1 of engel classification. 2 in class 2, rest had one each
 Conclusion: Following surgery approx half of patients were seizure free and Engel's favourable outcome was noted. The predictors of unfavourable outcome were younger age of onset and pronged duration and of epilepsy
 Keywords: Temporal lobe epilepsy, temporal lobectomy, amygdalohippocampectomy, outcome, extra temporal lobe epilepsy, extra temporal lobectomy
Highlights
IntroductionThe temporal lobe is the most epileptogenic region of the human brain and it is refractory to antiepileptic drug (AED) therapy
Ninteen consecutive patients operated for drug resistant Temporal lobe & extra temporal lobe epilepsy between 2019 and 2020, at our centre
The temporal lobe is the most epileptogenic region of the human brain and it is refractory to antiepileptic drug (AED) therapy
Summary
The temporal lobe is the most epileptogenic region of the human brain and it is refractory to antiepileptic drug (AED) therapy. Refractory to antiepileptic drugs is seen in 58%– 89% of patients.[1,2] Mesial temporal lobe (MTL), which integrates the limbic system[3,4,5] is the leading cause of being mesial temporal lobe sclerosis (MTLS), essentially hippocampal sclerosis.[6,7,8]. Due to the strong connections of the mesial temporal structures with the anterior and lateral temporal lobe in addition to other limbic regions, Temporal lobe epilepsy(TLE) most commonly manifests the semiology of staring and automatisms regardless of the seizure onset zone in lateral or mesial structures of the temporal lobe. The mean age of onset of epilepsy in study population was 14.9 ± 8 years. The predictors of unfavourable outcome were younger age of onset and pronged duration and of epilepsy Keywords: Temporal lobe epilepsy, temporal lobectomy, amygdalohippocampectomy, outcome, extra temporal lobe epilepsy, extra temporal lobectomy
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