Abstract
ABSTRACTSThe inflammatory process is described with particular reference to the cardinal signs, the microcir‐culatory changes and the mediators and modulators of inflammation. Mediators and modulars comprise targets for therapeutic intervention; and the arachidonic acid pathway, generating the eicosanoid group of compounds, is considered in detail. Most non‐steroidal anti‐inflammatory drugs (NSAIDs) of both carboxylic and enolic acid subgroups act partly and in some cases perhaps soley through inhibition of the enzyme cyclo‐oxy‐genase which is concerned with the generation of an important subgroup of eicosanoids, the prostaglandins. The wanted (therapeutic) and unwanted (side‐effects) actions of NSAIDs are considered together with their pharmacokinetic properties. The clinical pharmacology and therapeutic uses of NSAIDs in dogs and cats are described.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
