Pharmacology and chemical constituents of Hydnocarpus anthelmintica, Pierre: A review

Abstract

BackgroundHydnocarpus anthelmintica is a plant of the Hydnocarpus anthelmintica family, mainly found in Thailand, Southeast Asia, and other countries. It is also cultivated in Yunnan, Hainan, Guangxi, and other places in China, with a long medicinal history and a wide variety. PurposeTo review the pharmacological and chemical components of the plants of the genus Typhoon, providing a basis for their future scientific research and clinical application. MethodA comprehensive search was conducted on Pubmed, Embase, the Cochrane Library, Web of Science, CNKI, VIP, Sinomed, and Wanfang. ResultsThrough literature review, it is known that Hydnocarpus anthelmintica contains chemical components such as fatty oil, lignans, coumarins, and terpenes, which have the effects of dispelling wind and dampness, antibacterial and insect killing, lowering blood lipids and blood sugar, and anti-tumor. However, due to the toxicity of its raw materials, it is often combined with other Chinese medicinal herbs to prepare topical preparations for clinical use. ConclusionHydnocarpus anthelmintica has rich chemical components, extensive pharmacological effects, and a wide distribution of species. It is rich in medicinal resources and can be used in clinical practice alone or in combination with other Chinese medicinal herbs. Due to the toxicity of its raw products, it can be widely used in clinical practice after standardized processing.