Abstract
When focusing on specific tasks of GABAergic transmission, it is not very common to realize an extraordinary multi-functionality of the GABAergic system. In the present article, I would like to emphasize some aspects of the amazing versatility of GABAA receptors (GABAARs) and, on this background, to highlight novel findings by Mortensen et al. (2010) in a recent issue of The Journal of Physiology relating to distinct kinetics and pharmacology of synaptic and extrasynaptic GABAARs.
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