Abstract
Pharmacological effect of isoferuric acid and crude extracts CD-2-to-6, obtained from the chinese crude drug "Shoma" (the rhizome of Cimicifuga dahurica MAXIM.), was examined in mice and rats. Isoferuric acid showed a significant hypothermic, anti-pyretic, analgesic, and anti-edematous effect. CD4 strongly reduced writhing responses and carrageenin edema. CD6 showed significant hypothermic and anti-pyretic effects. It also showed a marked reduction of writhing responses. However, CD6 did not show any inhibition of carrageenin edema or analgesic effect using the tail pressure test. Only a slight reduction of writhing responses and dextran edema was found in CD5. CD2 showed a tendency of preventing lactic acid-induced anal ulcer, and a slight inhibition of carrageenin edema. The significance of these pharmacological results was discussed.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
