Abstract

Syrian rue ( Peganum harmala L., Zygophyllaceae ) has been used in traditional medicine of Central Asia, the Middle East, and Caucasus areas (Azerbaijan) for centuries, mainly as ritual and psychedelic plant. At full growth, this erect, dichotomously branched shrub is about 1 m in height with a dense foliage consisting of narrow, linear, pinnate leaves with acute spreading lobes, and small solitary, axillary, white flowers and globe capsules enclosing numerous angular seeds. All parts of the plant (including roots) contain alkaloids. The seeds contain β-carbolineses (harmine, harmalol and harman) with the active hallucinogen being the alkaloid harmine. The seeds contain a red pigment used for coloring wool and carpets and for use as a spice and, in traditional medicine, as valuable aphrodisiac.

Highlights

  • Syrian rue (Peganum harmala L., Zygophyllaceae) is a native plant of the Middle East that has become widely distributed in dry places throughout Central Asia and the Caucasus (Azerbaijan)

  • Syrian rue was used in traditional medicines of the Middle East, Central Asia, Azerbaijan, and India as ritual, psychedelic plant, for coloring wool in carpets, and as a spice [1, 2, 3, 4, 5, 6]

  • Mg and K are known as supplements used to reduce anxiety, depression, and effects of stress on central nervous system and cardiovascular system [3, 12, 19]. This study investigated both the macro and microelements in aboveground parts of P. harmala

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Summary

Introduction

Syrian rue (Peganum harmala L., Zygophyllaceae) is a native plant of the Middle East that has become widely distributed in dry places throughout Central Asia and the Caucasus (Azerbaijan) (as a wild plant and as a weed in grain plantations). Among the important phytochemicals of P. harmala β- carboline alkaloids constitute the most important constitutions of this plant This class of alkaloids is well known for several pharmacological activity include neuropsychological effects, that as an major investigated mechanism these compounds can facilities dopaminergic effects and intract with D1 and D2 dopamine receptors in brain observed some cross interaction between these chemicals and benzodiazepine receptors [13, 14, 15]. Mg and K are known as supplements used to reduce anxiety, depression, and effects of stress on central nervous system and cardiovascular system [3, 12, 19]. This study investigated both the macro and microelements in aboveground parts of P. harmala

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