Abstract
Overview of the Alzheimer's Disease Pathology and Potential Therapeutic Targets.- Trial Designs and Outcomes to Monitor Novel Therapeutics in Alzheimer's Disease.- The Pharmacological Treatment of Alzheimer's Disease with Cholinesterase Inhibitors and Memantine.- M1 Muscarinic Agonists: A Comprehensive Therapy Against Major Hallmarks of Alzheimer's Disease.- Cholinergic Neurodegeneration in Alzheimer's Disease: Basis for Nerve Growth Factor Therapy.- The Rationale for Glutamatergic Therapy in Alzheimer's Disease.- Secretases as Pharmacological Targets in Alzheimer's Disease.- ?-Secretase as a Target for Alzheimer's Disease.- The Rationale for an Immunological Approach to Alzheimer's Therapeutics.- Neuroinflammation, Alzheimer Disease, and Other Aging Disorders.- Nonsteroidal Anti-inflammatory Drugs (NSAIDs) and Derived A?42-Lowering Molecules for Treatment and Prevention of Alzheimer's Disease (AD).- The Potential Application of Antioxidant Agents in Alzheimer Disease Therapeutics.- Apolipoprotein E: A Potent Gene-Based Therapeutic Target for the Treatment of Sporadic Alzheimer's Disease.- Tau Pathology as a Target in Alzheimer's Therapeutics.- Design of Inhibitors of Amyloid-? Misfolding and Aggregation for Alzheimer's Therapy.- Potential Applications of Glycosaminoglycan-Related Compounds in Alzheimer's Disease.- Multifunctional Neuroprotective Drugs for the Treatment of Alzheimer's Disease.- Interpreting Clinical Studies of Putative Therapeutics for Alzheimer's Disease: The Case of Statins and NSAIDs.
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