Abstract
Objective: The plant Cannabis indica is a very popular and well known plant across the globe since thousands of years. In India also it is even more popular as bhang or marijuna from ancient time. A quite descriptions of this plant is written in various ancient books like the granths, vedas, puranas, ayurvedic books, dravyaguna, etc.. Number of medicinal properties have been described for different parts of the plant like flower buds(Ganja), Leaf(Bhang) & Leaf wax(Charas). All the parts of this plant have potent and complex psychotropic properties along with some additional therapeutic actions on different body systems. Here we have fond some opportunities to evaluate herbal extracts of leaves for having aphrodisiac potential. Method: The aphrodisiac activity of Cannabis indicaleaf extracts (Pet.ether, methenol & aqueous) were evaluated in male albino rats. Extracts were administered at a dose of 150mg/kg body weight. At a interval of 0,7,14,21 & 28 day several sexual behavior parameters were determined. At the end serum testosterone and FSH level were also determined. Results: This study also contributes to the pharmacology of aphrodisiacs as the plant Cannabis indica leaf extracts has significant effects on sexual physiology. It has shown effects on sexual behaviors as well as significant change in gonadotropin hormone labels in animal blood serum. Conclusion: This study provides a strong experimental evidence for its aphrodisiac use.
Highlights
Infertility is one of the major health problems couple's lives; approximately 30% of couple’s infertilities are due to male factors
This study contributes to the pharmacology of aphrodisiacs as the plant Cannabis indica leaf extracts has significant effects on sexual physiology
Sexual behavior study Several female proceptive and male precopulatory behavior parameters were observed from the cage side when the extract treated male rats were introduced to the receptive female rats
Summary
Infertility is one of the major health problems couple's lives; approximately 30% of couple’s infertilities are due to male factors. Around 10-14% Indian population suffering from infertility. 27.5 million ones are trying to conceive suffering from infertility in India. WHO estimates that there are 60 -80 million infertile couples worldwide.[1] Loss of interest in sex or problems with sexual arousal makes most individuals experience and express discomfort in their sexual behavior. Such concerns or changes may arise from an illness or disability, medication or surgical procedure, changes accompanying the aging process[2], relationship difficulties[3] performance anxiety[4], or a combination of any of these factors. There are three basic types of sexual dysfunction; disorders of desire takes the form of inadequate sexual desire (libido) in both sexes[5] disorders of excitement (or arousal) in men, impotence[6] disorders of orgasm, includes difficulty achieving orgasm in both men and women
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