PHARMACOLOGICAL ACTIVITIES OF Nymphaea pubescens WILLD. EXTRACTS

Saravanan Vivekanandarajah Sathasivampillai,Pholtan Rajamanoharan

doi:10.26480/asm.02.2021.73.74

Abstract

Nymphaea pubescens Willd belongs to the Nymphaeaceae family. This plant species is used to treat various diseases including diabetes, diarrhea, dysentery, hemorrhages, and indigestion in traditional medicines around the world. Compounds like Arbutin, D-malic acid, Ergosterol, Fumaric acid, and Gluconic acid have been isolated from N. pubescens. As N. pubescens pharmacological activities are not systematically reviewed, this review is intended to analyze, recap, and document the reported bioactivities of N. pubescens. Appropriate published papers were obtained using the Web of Science, Scopus, PubMed, and ScienceDirect databases from 1900 to June 2021. Until now, anticancer, antidementia, antidiabetic, antihepatotoxic, antiinflammatory, antioxidant, and hypolipidemic activities have been reported for different parts of N. pubescens. Remarkably, hitherto, no pharmacological active compound has been isolated from N. pubescens. This review provides a foundation for future research on this plant species.

Highlights

Nymphaea pubescens Willd. [synonyms: Castalia pubescens (Willd.) Wood; Nymphaea devoniensis Hook.; Nymphaea purpurea Rehnelt & F.Henkel; and Nymphaea semisterilis Lehm.] belongs to the Nymphaeaceae family
N. pubescens is native to Sri Lanka, India, New Guinea, Philippines, Australia, Bangladesh, Vietnam, Cambodia, Thailand, China, Laos, Pakistan, Myanmar, and Malaysia and it has been introduced into Cuba (Kew Science, 2021)
Anticancer, antidementia, antidiabetic, antihepatotoxic, antiinflammatory, antioxidant, and hypolipidemic activities have been reported for different parts of N. pubescens (Acharya et al, 2018; Aimvijarn et al, 2018; Angadi et al, 2013; Debnath et al, 2013; Karthiyayini et al, 2011; Shajeela et al, 2012)

Summary

INTRODUCTION

Nymphaea pubescens Willd. [synonyms: Castalia pubescens (Willd.) Wood; Nymphaea devoniensis Hook.; Nymphaea purpurea Rehnelt & F.Henkel; and Nymphaea semisterilis Lehm.] belongs to the Nymphaeaceae family. [synonyms: Castalia pubescens (Willd.) Wood; Nymphaea devoniensis Hook.; Nymphaea purpurea Rehnelt & F.Henkel; and Nymphaea semisterilis Lehm.] belongs to the Nymphaeaceae family. N. pubescens is native to Sri Lanka, India, New Guinea, Philippines, Australia, Bangladesh, Vietnam, Cambodia, Thailand, China, Laos, Pakistan, Myanmar, and Malaysia and it has been introduced into Cuba (Kew Science, 2021). This plant species is used to treat various diseases including diabetes, diarrhea, dysentery, hemorrhages, indigestion, eye illnesses, jaundice, cancer, and inflammation in traditional medicines around the world (Karthiyayini et al, 2011; Nadkarni, 1996; Sathasivampillai et al, 2017, 2018, 2016, 2015). As N. pubescens pharmacological activities are not systematically reviewed, this review is intended to analyze, recap, and document the reported bioactivities of N. pubescens

MATERIALS AND METHODS

RESULTS AND DISCUSSION

CONCLUSION