Abstract
Hyperoside (quercetin-3-O-D-galactoside) is a flavonol glycoside which has been isolated from different plants. It has different pharmacological actions such as anti-inflammatory, anti-depressant, neuroprotective, cardio-protective, anti-diabetic, anti-cancer, anti-fungal, radio-protective, gastro-protective, and antioxidant activities. Studies on its pharmacokinetic (PK) properties revealed that it is a stable compound with no significant gender variation in its activities. Other significant details on its pharmacological properties and information for future investigations on its components are provided. Keywords : Hyperoside; Anti-inflammatory, Antidepressant, Neuroprotective, Antidiabetic, Anticancer, Antioxidant, Cytochrome P450
Highlights
Natural products have recently attracted much attention in drug discovery and food supplement research because they are frequently used due to their chemical diversity and potent bioactivities
Flavonoids are plant polyphenols found in herbs, vegetables and fruits
Flavonoids comprise a large group of polyphenolic with a benzo-γpyrone structure
Summary
Natural products have recently attracted much attention in drug discovery and food supplement research because they are frequently used due to their chemical diversity and potent bioactivities. Flavonoids are plant polyphenols found in herbs, vegetables and fruits They are well known for their hepatoprotective, cardioprotective, antipyretic, analgesic, and antiinflammatory activities [1]. Flavonoids comprise a large group of polyphenolic with a benzo-γpyrone structure. They are synthesized by the phenylpropanoid pathway. Hyperoside (Figure 1), known as quercetin3-O-D-galactoside, is a flavonol glycoside present in a variety of vegetables and fruits [3,4]. It has been isolated from various medicinal
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