Abstract
Abstract PPP-Trimethyl-2-(2,6-xylyloxy)ethylphosphonium bromide (PTM10; phospho-TM10), the phosphorus analogue of xylocholine (TM10), has been found to possess local anaesthetic, α-adrenoceptor and ganglion blocking properties. It also shows a blocking action at the neuromuscular junction but has no detectable adrenergic neuron blocking properties. The relation of these results to the ‘cholinergic link” hypothesis of Burn and Rand is discussed.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Published version (
Free)
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
