Abstract
Successful establishment of enteral feedings is major goal in the treatment of very low-birthweight infants, but functional immaturity of the gastrointestinal tract may hamper such efforts. Prokinetic agents often are used in an attempt to overcome the functional immaturity by speeding up gastric emptying and increasing small intestinal motility. This brief review examines the currently used candidate drugs: erythromycin, metoclopramide, and domperidone, as well as the potential role for prebiotics and probiotics.
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