Abstract
A large number of compounds can modify the function, synthesis, or metabolism of steroid hormones. These are not necessarily otherwise related chemically or pharmacologically. The drugs used as examples in this review were selected to show the wide variety of potential sites and modes of action. While many compounds have been shown to interfere with one or another step in the biosynthesis of corticosteroids, the number of known substances having any profound effect on gonadal steroidogenesis is surprisingly few. On the other hand, many more compounds are known either to mimic or modify the end‐organ response to gonadal than to adrenal steroids. The field of endocrine pharmacology is being rapidly widened as systematic searches are now being made for drugs which affect endocrine function either as a primary or incidental action.
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