Abstract
We measured the serum levels of tamoxifen and 5 of its metabolites in serum from 7 premenopausal and 9 postmenopausal women during the first 56 days of treatment. The serum levels of N-desdimethyltamoxifen were higher in postmenopausal women compared to premenopausal women ( P < 0.02). A similar trend was observed for N-desmethyltamoxifen ( P = 0.06).
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