Abstract
There are no established guidelines for evaluating and managing those taking psychotropic medications postoperatively. This study reviews the pharmacokinetic changes in antidepressants after bariatric surgery and their clinical implications. A systematic search found 7 relevant articles out of 245, indicating significant alterations in the bioavailability and metabolism after surgery. Many patients require increased medication doses postoperatively to maintain therapeutic effects, with a gradual return to baseline within 6 to 12 months. The reviewed studies emphasize the importance of close monitoring and adjustments in medication formulations and dosages. The findings offer valuable insights for health care providers working with this patient group.
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