Pharmacognostic Study of Ehretia acuminata R.Br.

Abstract

Ehretia acuminata, commonly known as “Puna” in Pakistan, is from the Boraginaceae family and is used in ecological, medicinal, and agricultural sectors. The current study was conducted to assess the pharmacognostic potency of bark extracts from E. acuminata. The crude distilled water, ethanol, and chloroform extracts signified a concentration-dependent increase in intestinal mobility of the experimented animal, and the plant delivered methodical proof for its pharmacological usage as an antispasmodic drug. The bark distilled water, bark ethanol, and bark chloroform extracts revealed (11±1, 9±1, and 11±1) antispasmodic potential at (300 mg/kg). The distilled water, ethanol, and chloroform extracts also showed analgesic potential in the present study and the results were concentration dependent. The bark distilled water, bark ethanol, and bark chloroform extracts revealed the (10±1,16±1, and 11±1) analgesic potential at (300 mg/kg). The distilled water, ethanol, and chloroform extracts also showed the muscle relaxant potential in this study and the results were concentration dependent. The Bark distilled water, Bark ethanol, and Bark chloroform extracts revealed the (6±1, 5±1, and 5±1) at (300 mg/kg). While the distilled water, ethanol and chloroform extracts did not show acute toxic effects against the tested animal mice. In this study, bark extracts of E. acuminata showed pharmacological potency in experimental animals. The plant delivered scientific proof for its pharmacological usage as an antispasmodic, acutely toxic, muscle relaxant, as well as an analgesic drug.