Pharmacogenetics: Therapeutic regimen in hypertension

Abstract

Pharmacogenetics in hypertension is a field of study that aims to understand how interindividual genetic variability can influence the response to medications used to treat high blood pressure, which is a common cardiovascular condition. This approach aims to analyze the pharmacogenetic impact on arterial hypertension. Currently, a wide range of genetic variants have been identified that can affect an individual's response to antihypertensive medications. For example, some genes can influence how the body metabolizes medications, affecting the dosage needed to achieve adequate blood pressure control. Other genes may be related to susceptibility to adverse side effects. Pharmacogenetics in hypertension allows doctors to make more informed decisions about which medication to prescribe to a patient based on their genetic profile. This can increase the effectiveness of the treatment and reduce the likelihood of unwanted side effects. Additionally, this approach may be particularly useful in cases of refractory hypertension, where patients do not respond to conventional therapies. Pharmacogenetics in hypertension is a growing field that seeks to personalize the treatment of this common cardiovascular condition. By understanding how individual genes affect responses to medications, doctors can make treatments more precisely to improve blood pressure control and reduce side effects. However, it is important to note that, although promising, this approach is still in development and is not widely available in clinical practice.