Abstract
The paper by Twardowschy et al.1 is certainly opportune since phenytoin is considered extremely effective as a drug treatment for focal seizures and focal epilepsy syndromes2 and it is still one of the most used antiepileptic drugs worldwide, including in the USA3. Experts in the field of epilepsy have a tendency to reduce the use of phenytoin mainly due to its adverse effects and because it is a potent inducer of the hepatic microsomal system which may lead to serious potential drug [...]
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