Abstract
In this study, we were provided universal considerations for the setting up and carry out of pharmacoepidemiological studies of drug use for disorders like Osteoarthritis, Hypertension, Hyperlipidemia, Hypothyroidism, Depression, and Osteoporosis in geriatric patient. The study method was focused on monitored and categorized the prescriptions of geriatrics from 650 patient in Madapalle and Puganur region of Andhra Pradesh, Identified and prepare the list of drugs, which were inappropriately prescribed and used in geriatrics by using Revised Beers criteria and also assess the Activities of Daily Living (ADL) by using Modified Barthel Index (MBI). Identify any drug-drug interactions among the drugs used in geriatrics. We were reported the adverse drug reactions appeared in geriatrics and the various treatments that the patients are received with different co-morbidity disease with the assessment of drug exposure, and ascertainment of PIM, PPO STOPP, START criteria and MBI outcomes. Characteristic of statistics sources include evaluation of complete history of drug use in elderly patient with co-morbidity condition, allowing approximate of collective exposure. Result data from beers criteria with PIM, modified barthel index are preferable, but elderly patient treatment data from reliable sources, for example, patient or pathology registries, and medical records are also considered. We present report to showed poly-pharmacy effects of drug use on elderly patient improvement and converse the need for employing STOPP and START criteria of PIM and PPO to avoid undesirable drug reaction causation. We emphasize that a study design of beers criteria always be considered and result of Modified barthel index shows the dependency rate in elderly patient. We also underline the need for Comorbidity analyses in geriatric patient and drug usage, as drug utilization in geriatric are prone to dose and number of drugs in treatment dependent. In the main, studies of Prescription analyses like polypharmacy, PIM, PPO in prescription should explore risk Geriatric patient, the present study reveal the PIM and PPO of in prescription from six hundred and fifty geriatric patient. We conclude the pharmacoepidemiological studies of elderly patient are likely to develop significantly in the coming years, due to the rising mortality of long-term drug exposures and less awareness of poly-pharmacy result, the increasing perform of multinational studies, permiting studies of rare and common disease in elderly people, types of medication and procedural development specifically addressing geriatric treatment and long-term outcomes.
Highlights
Pharmacoepidemiology studies investigate the use and effects of drugs and other medical products in populations and the field has made significant step in adults, same way there is a national need for pharmacoepidemiology studies in geriatric
The present study focused on comparisons of studies investigating inappropriate drug use among older people are vulnerable by different aspects of drug use, both gender of populations in specific region in Andhra Pradesh and different settings studied
The most common chronic disease identified as Osteoarthritis in 68% of the population and the medical record of female shows potentially inappropriate medications (PIMs) higher than the males so the necessary aspect of drug therapy should analyze to avoid PIM in elderly female population and it may influenced by specific drug therapy in female like calcium, hormonal related drugs and anatomy and physiological variation in female
Summary
Pharmacoepidemiology studies investigate the use and effects of drugs and other medical products in populations and the field has made significant step in adults, same way there is a national need for pharmacoepidemiology studies in geriatric. The overpowering majority of patient interactions with the health care system involve decisionmaking about drug therapy. In order to ensure towering care, it is important for decision-makers like patients, caregivers, clinicians and third-party payers to know whether a certain drug therapy provides value for the money. The pharmacoepidemiology studies in different population can be used to help set priorities for the provision of health care management at individual and national levels [1]. The World Health Organization said pharmacoepidemiology studies apply epidemiological frequency, Pattern, methods and knowledge to study the clinical use and effects of drugs in human being, as well as nonprescription drugs, biological Preparations and medical equipments
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