Abstract
Tumbarello et al (Predictors of Mortality in Patients with Bloodstream Infections Caused by Extended-Spectrum-β-Lactamase-Producing Enterobacteriaceae: Importance of Inadequate Initial Antimicrobial Treatment, AAC June 2007) showed higher mortality with ESBL bacteraemia where treatment is initiated with inappropriate antibiotics (60% vs. 20% approximately). Dellinger, Levy and Carlet et al state that severe sepsis causes mortality between 28-50% (Surviving Sepsis Campaign, Crit Care Med 2008). Our bacteraemia surveillance shows that ESBL producers are becoming more prevalent.
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