PHARMACEUTICO-ANALYTICAL STUDY OF JATYADI GHRITA AND JATYADI KER TAILA WITH SPECIAL REFERENCE TO THEIR HPTLC FINGERPRINTS PROFILE

Abstract

Jatyadi Ghrita is a ghee based Ayurvedic formulation useful for sravi (secretory), gambhira (deep), Dushta Vrana (contaminated wound) by external application by shodhana (cleaning) and ropana (healing) as per the classical texts of Ayurveda. Now day’s pharmacies are using coconut oil instead of ghrita for preparation of Jatyadi Ker Taila, but remaining contents are same as that of Jatyadighrita as quoted in our Samhitas. Hence a comparative study on Jatyadighrita as per classical text and Jatyadi Ker Taila (modified method by using coconut oil replacing ghrita) to know their physico-chemical properties. The physicochemical tests performed on different samples of Jatyadi Ghrita and Jatyadi Ker taila such as specific gravity, acid value, saponification value, Total fatty matter, melting point, viscosity etc. Further standardization by instrument analysis performed on HPTLC for finger printing profile. Comparative evaluation of above parameters shows that Ker taila (coconut oil) can be used as better substitute of ghrita for the preparation of Jatyadi formulation. Related physicochemical tests and HPTLC profile clearly shows the more stability of formulation and increased number of secondary metabolite extraction in Ker taila than ghrita. Possibly the above results denote best substitution of classical formulation Jatyadi ghrita is Jatyadi Ker taila (by using coconut oil replacing ghrita).