Pharmaceutico-analytical Study of Patolakaturohinyadi Ghanavati - A Poly Herbal Formulation

Abstract

Background Patolakaturohinyadi Kashaya is a polyherbal preparation which is widely used for many of the chronic disease conditions like Kushta Yakrit Vikara Medoroga etc. In chronic disease conditions the duration of medicine intake will also be for longer periods. Though the Patolakaturohinyadi Kashaya is a very potent medicine its effect can be noticed only when consumed for the number of days as suggested by the physician. Many a times this becomes a challenge for the patients because of its bitter taste. Also as it is available in liquid form transport from one place to another becomes difficult.Aim To perform Pharmaceutico-analytical study of Patolakaturohinyadi Ghanavati Methods The present study was taken up for the preparation of ghanavati of Patolakaturohinyadi Kashayam of shodhaniya adhyaya of Astanga Hridaya Sutrasthana. The prepared vati was subjected to physicochemical and phytochemical analysis HPTLC microbial load analysis as per the WHO guidelines. Efforts were made to set the analytical standards for the Patolakaturohinyadi ghanavati which were not reported till date.Results Loss on drying 6.268 ash value 46.222 acid insoluble ash 1.925 water soluble extractive 77.972 alcohol soluble extractive 28.557 hardness 6.0 kgcm friability 0.164 disintegration 25 min pH 6.12 in HPTLC of Patolakaturohinyadi Ghanavati maximum four sports at short UV and long UV were noted. Microorganisms in the formulation were found to be 38 CFUmL.Conclusion The study concludes that the formulation of Patolakaturohinyadi Ghanavati contains all good characteristics of an ideal vati and also the formulation is of good quality and purity.