Pharmaceutico- Analytical Study of Abhra Sindoora

Abstract

Background: Abhra Sindoora[1] (ABS) is a unique Rasa Yoga with having more potent and indication in Tridoshahara, Swasa, Kasa etc. It is one of the important classical Kupipakva Rasayana containing Hingulotha Parada (purified mercury), Shuddha Gandhaka (purified sulfur) and Dhanyabhraka in 1:1:1 proportion. Aim: Pharmaceutico-Analytical study of Abhra Sindoora. Materials and Methods: Hingulotha Parada (purified mercury), Shuddha Gandhaka (purified sulfur) and Dhanyabhraka are used to prepare Kajjali and lavigated with Vatankura (leaf buds of Ficus bengalensis), Swarasa (juice) and Arka (Calotrapis procera) ksheera (milk). This Kajjali is processed by Kupipakva method. Results and Conclusion: The current trend in applied instrumental medical research encourages good medical practice, clinical and research based drug analysis. The main aim of analytical study is to find out working standards for the formulations and safe use of therapeutics. Abhra Sindoora was prepared in 48 hours with 28% yield. It was also characterized by using modern instrumental analysis like XRD, SEMEDX, EDXRF, FTIR and PARTICLE ANALYSIS. The SEM analysis evaluated that prepared Abhra Sindoora has particles in nanometers, least being 14.87nm. SEMEDX study confirmed the presence of C, O, Si, S, K, and HgM. XRD study confirmed the presence of Hg3.00S3.00 in hexagonal crystal system. The EDXRF analysis evaluated the presence of K, Ca, Ti, Mn, Fe, S, Br and Hg. FTIR analysis shows organic compounds with functional groups like secondary amines, Nitro, Carboxylic acids, Bromine, Esters, Alkines, and Iodides etc.