Abstract
The drugs with poor solubility results in delayed absorption which consequently affects the bioavailability. There are many drugs which are having good therapeutic value but not used commercially because of this reason. The permeation enhancers are therefore being utilized to counter this problem. There are many such synthetic and natural materials which have the ability to enhance the drug permeation rate. The essential oils, alcohols, terpenes, azoles and many other chemical derivatives have the capability to be used for permeation enhancer. The present review work suggested the role of permeation enhancer in the pharmaceutical world.
Highlights
Nature has provided the humanities with the wide range of natural substances which can be used in a number of ways
This hitch has confined the use of many drugs, which is potentially and therapeutically very active. To counter this problem the researchers have tried to incorporate the permeation enhancers. These permeation enhancers can be of natural origin or semi-synthetic or even synthetic too
The present work tries to focus on the natural permeation enhancer used in the pharmaceutical world
Summary
Nature has provided the humanities with the wide range of natural substances which can be used in a number of ways. The present work tries to focus on the natural permeation enhancer used in the pharmaceutical world. 8. Must have the capacity to be tested in vitro for better results of final formulations. The mechanism of action of permeation enhancer depends upon the technique through which it works.
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