Abstract

Foreword Preface Introduction Process Research and Development in the Pharmaceutical Industry: Origins, Evolution and Progress Active Pharmaceutical Ingredients: Structure and Impact on Synthesis Rapid Early Development of Potential Drug Candidates Route Design and Selection The Importance of Green Chemistry in Process Research and Development Kinetic Approaches for Faster and Efficient Process Development The Design of Safe Chemical Reactions - It's No Accident Physicochemical Data Requirements for the Design of Fine Chemical Processes - Acquisition and Application Liquid-Liquid Extraction for Process Development in the Pharmaceutical Industry Development Enabling Technologies The Analytical Interface and the Impact on Pharmaceutical Process Development Materials Science - Solid Form Design and Crystallisation Process Development Technology Transfer of API Future Trends and Challenges

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