Abstract
Objective The objective of this study was to compare the role of phakic foldable angle-supported intraocular lens (IOL) with laser in-situ keratomileusis (LASIK) for correction of moderate and high myopia. Patients and methods Twenty eyes received phakic foldable angle-supported IOL, and 20 eyes received LASIK. Main outcome: slit-lamp microscopy, manifest refraction, uncorrected and best-corrected visual acuity (BCVA), pentacam, IOL calculation (for group 1) with the IOL Master, and specular microscopy were performed before surgery, and 3 and 6 months after surgery. Results At 6 months, the mean spherical equivalent refraction was −0.31 ± 0.44 D (ranging from 0.5 to −1.25 D) in Cachet eyes and −1.04 ± 0.94 D (ranging from 0.25 to −3.5 D) in LASIK eyes. Neither Cachet eyes nor LASIK eyes lost two or more LogMar lines of preoperative BCVA. No Cachet eyes and one LASIK eye lost one LogMar line of preoperative BCVA. The mean percentage of endothelial cell loss in the Cachet group was 8.0% at 6 months, whereas in the LASIK group it was 0.84% at 6 months. Conclusion In this study, Cachet lens implantation and LASIK were found to be effective for the correction of moderate and high myopia. The endothelial cell loss in Cachet eyes was high, which makes it less safe compared with LASIK.
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