Abstract
AbstractIn this paper, pH‐responsive fluorescent poly(amino ether ester)s with reversible “on–off” switching fluorescence and concentration‐dependent emission behavior were reported. A remarkable difference fluorescence behavior was observed at diverse polymer concentrations with pH values. Moreover, at all investigated concentrations, poly(amino ether ester)s can respond to acid pH and exhibit extreme acid‐induced fluorescence quenching phenomenon. Dynamic light scattering and transmission electron microscopy analyses confirmed that the fluorescence quenching phenomenon is due to the aggregation, which was caused by the protonation of tertiary amine groups in poly(amino ether ester)s under extreme acidic conditions. Interestingly, the quenched fluorescence can be completely recovered by adding an alkaline solution, thereby enabling an “on–off” switch function by adjusting the pH value. Most importantly, the pH‐responsive fluorescent poly(amino ether ester)s exhibit good biocompatibility and cellular imaging, and its cellular imaging function is highly sensitive to acid pH. Thus, this study opens a new idea for the preparation of amine‐based fluorescent polymers as stimuli‐responsive fluorescent probe for cellular imaging, drug delivery, and disease diagnostics.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
