PGD Vs. Abortion: A Deep View on “Authority” and “Necessity” in Cases of Predictable Fetal Abnormality

Abstract

The fast-growing utilization of Nanoparticles (NPs) in countless industries unlocked the potential for more research on NPs possible toxicity of both normal and pathological cells. In the current study, We focused on the cytotoxic effect of Zinc Oxide NPs (ZnO NP), Titanium dioxide NPs (TiO2 NP) and the mixture of both NPs with three different molar ratios of ZnO/TiO2 1:1, 1:2 and 2:1 to different types of cells (African green monkey kidney cells, human lung fibroblast and macrophagic cells differentiated from rat’s blood monocytes and epithelial carcinogenic cells. The NPs were prepared with average sizes <25 nm and characterized by X-ray Diffraction (XRD), High- Resolution Transmission Electron Microscope (HRTEM), Fourier Transform Infrared (FT-IR). Our results showed that Zinc Oxide provided a high toxic effect on normal cells and epithelial carcinoma, while Titanium dioxide showed slight cytotoxicity. Adding a mixture of both NPS with different ratios caused various toxic effects on both normal and cancer cells depending on their ratio. Addition of Titanium dioxide to Zinc oxide reduced the toxicity of zinc oxide in normal cells and improved the cell immune response, i.e., adding Titanium dioxide to Zinc Oxide had improved its characteristics in cancer cell control depending on the ratio added. On the other hand, Nanomaterials have distinct features matched to their bulk counterparts. A current feature that these NPs exhibit an antimicrobial behavior against pathogenic bacteria. In this study, we also investigate the antimicrobial vigor of ZnO, TiO2 and their various ratios NPs against certain Gram-positive and Gram-negative bacteria.