Abstract

After a roller coaster of conjecture, cancer drugmaker Seagen has finally been acquired. Pfizer agreed March 13 to buy the firm, formerly Seattle Genetics, for $43 billion. The deal is expected to be completed in late 2023 or early 2024. Seagen specializes in antibody-drug conjugates (ADCs), which link disease-fighting molecules to tumor cell–targeting antibodies. The goal of ADCs is to deliver powerful therapies specifically to tumor cells, sparing healthy cells from collateral damage. “Oncology is a core therapeutic area for Pfizer, and we believe the proposed combination with Seagen will enhance our position in this important space while significantly advancing the global fight against cancer,” Pfizer CEO Albert Bourla said in a March 13 call to discuss the deal with analysts and investors. He also emphasized the opportunity to combine Pfizer’s and Seagen’s assets into new therapeutic regimens, citing Seagen’s breast cancer drug Tukysa and Pfizer’s multiple myeloma drug candidate

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