Abstract
Introduction: Blood donors (BDs), in most cases, tolerate the whole blood donation procedure well. However, occasionally adverse reactions (ARs) may occur. ARs often have a negative impact on donors return. Therefore, the staff of transfusion institutions must be educated and properly trained to recognize and take care of BDs who experience ARs before, during or after the procedure. The incidence of ARs is about 1,4%. Aim: To determine the frequency and severity of ARs that occurred among BDs on the territory of Vojvodina, analyze the age and profile of donors in whom they were recognized, indicate possible prevention of ARs. Material and methods: In a retrospective study, the records of ARs among whole BDs at the Blood Transfusion Institute Vojvodina, from January 1 2017, until December 31, 2021 were analyzed. Demographic data of the donors were obtained from the Institute's information system. The data were analyzed according to the time and manner of occurrence and the severity of ARs. Results: During the study period there were 194 425 blood donations. The ARs were identified in 2722 (1,4%) donations. The incidence was 14 in every 1000 donations. BDs who suffered ARs were 28,0 ± 8,3 years old, 1881 (69,1%) were male, 841 (30,9%) were female, while 1908 (70,1%) donated blood for the first time. In 2396 (88,03%) BDs vasovagal reaction occurred, 737 (27,08%) experienced nausea, 363 (13,33%) suffered syncope, 221 (8,13%) developed hyperventilation, 64 (2,34%) gained hematoma. Severe ARs in the form of collapse with convulsions were experienced by 12 (0.44%) donors. In multiple BDs, ARs were significantly less frequent (p<0,05). Conclusion: Although the number of donors with ARs in institution is low, it is necessary to monitor them, react promptly in case of their occurrence and minimize the risks of occurrence, primarily through education and preparation of donors for the whole blood donation procedure.
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